ACE and diabetes mellitus: Risk factor domains for the trivariate outcomes include the following: demographic (age, sex, race); behavioral (current smoker, body mass index [kg/m2]); cardiovascular factors (systolic and diastolic blood pressure [SBP/DBP], high BP (BP > 130/80 mmHg), angle-brachial index [ABI]), laboratory measures (hemoglobin A1c [HbA1c], calcium, creatinine, glucose), use of angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) therapy, diabetes, hypertension, and history of CVD.