TP53 and cancer: Gene expression profiling and pathway analysis in C1QBP depleted cells compared to the control revealed that a total of 236 differential expression genes (DEGs), including 119 upregulated DEGs and 117 downregulated DEGs, and were predicted to enrich in Herpes simplex virus 1 infection, Pathways in cancer, PI3K-Akt signaling pathway, Apoptosis, Apoptosis-multiple species and p53 signaling pathway.