Jingbo Xue et al. found that the level of lncRNA SNHG14 increased in a time-dependent manner during the pathogenesis of osteoporosis, and regulated the expression of Mef2c through miR-493-5p, while P38/Mef2c was proved to be associated with autophagy activation [48]. The gene discussed is MEF2C; the disease is osteoporosis.