Exposure of SH-SY neuronal cells with the Paraquat (PQ) oxidative reagent, induced higher circSLC8A1 in a dose-dependent manner while the decreased Solute Carrier Family 8 Member A1 (SLC8A1) protein levels, also circSLC8A1 via regulating miR-128 is linked to PD modulating oxidative stress (Hanan et al., 2020). This evidence concerns the gene SLC8A1 and Parkinson disease.