SNCA and Parkinson disease: It has been proved that 5–10% of PD are familial and can be influenced by a pattern of genetic inheritance such as autosomal-dominant in (LRKK2, SNCA, VPS35) and autosomal recessive mutation in (DJ-1, PINK1, Parkin) (Cherian and Divya, 2020; Kim and Jeong, 2020).