Flow cytometry analysis revealed that tumor-infiltrating macrophages (CD11b+F4/80+) in 1,25(OH)2D3 group significantly increased from 8.13% (PBS) to 33.4% (p < 0.01), while significantly decreased in suramin group (21.7%, p < 0.05) and combination group (17.95%, p < 0.001) (Figure 7E). The gene discussed is ITGAM; the disease is neoplasm.