A second cluster (ELF2, ETS1, FOXO1, ERG, TAL1, FOXO3, FOXJ3, EBF1, and ZEB1) includes TFs regulating a diverse set of biological processes, including the transcriptional misregulation in cancer KEGG pathway and the KEGG prostate cancer pathway (Fig. 3C). The gene discussed is FOXO3; the disease is prostate cancer.