Some studies reported that polymorphisms of KCNQ1 (rs2237892, rs2237895, and rs2074196) and KCNJ11 (E23K) were associated with GDM (146–149), but others found that gene polymorphisms of KCNJ11 (rs5219) and KCNQ1 (rs2237892, rs151290, rs231841, and rs7929804) were not significant risk factors for the development of GDM (150–152). The gene discussed is KCNJ11; the disease is gestational diabetes.