HR: hazard ratio, CI: confidence interval, BMI: body mass index, ASA-PS: American Society of Anesthesiologists physical status, CEA: carcinoembryonic antigen, CA19-9: carbohydrate antigen 19-9, PNI: prognostic nutritional index, CAR: C-reactive protein-to-albumin ratio, SUVmax: Standardized Uptake Value Max, PET-CT: Positron Emission Tomography-Computed Tomography, CD: Clavien–Dindo, tub: tubular adenocarcinoma, por: poor differentiated adenocarcinoma, muc: mucinous adenocarcinoma. The gene discussed is CEACAM5; the disease is tubular adenocarcinoma.