Similarly, Xinfeng capsule (XFC) has been shown to alleviate inflammation and hypercoagulability in RA by regulating the lncRNA down syndrome critical region 9 (DSCR9)/ribosomal protein lateral stalk subunit P2 (RPLP2)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B, PKB (AKT) axis (21). This evidence concerns the gene AKT1 and thrombophilia.