Using IFA to test COVID-19 positive serum samples, 96.1% (148/154) were ANCA negative on ethanol-fixed substrate slides, while 1.9% (3/154) were pANCA-positive, 1.2% (2/154) were cANCA-positive, and 0.6% (1/154) were atypical ANCA-positive. The gene discussed is PRTN3; the disease is COVID-19.