IL7 and myelodysplastic syndrome: To more broadly quantify this hematopoiesis-supporting gene expression pattern of stromal cells, we aggregated gene programs of hematopoiesis-supporting factors (Cxcl12, Kitl, Il7, and Igf1) and observed a significant increase in this gene expression signature in the most primitive CAR cells upon engraftment with MDS than in those with HY (Figure 1F).