The clustering analysis revealed seven cell types enriched in tumor tissues (including CD4_Exhausted, CD8_Teff, CD8_Tc17, Treg_Suppressive, Cycling T cells, CD8_GZMK_ZNF683 and CD8_Exhausted), and five cell types enriched in normal tissues (including CD8_Naive, CD4_Naive, Treg_IL10, CD4_Bood_Tcm, CD8_Blood_Teff). Here, CD8A is linked to neoplasm.