Among the 46 patients diagnosed with IDH-wildtype glioblastoma, 20 cases were in the low-level expression group (Ki-67 expression level: 12.50 ± 3.93%), consisting of 6 males and 14 females, with an average age of 52.90 ± 9.50 years. The gene discussed is MKI67; the disease is glioblastoma.