MRPL58 and osteosarcoma: For example, a similar mitochondrial translation release factor mitochondrial ribosomal protein L58 (Mrpl58), also referred to as immature colon carcinoma transcript-1 (Ict1), has been linked to various types of cancers (Chicherin et al., 2021), including colorectal cancer (Lao et al., 2016), osteosarcoma (Pan et al., 2021), breast cancer (Peng et al., 2018; Wang et al., 2017a), lymphoma (Xie et al., 2017) and numerous other cancers (Chang et al., 2017; Huang et al., 2014; Li et al., 2018; Tao et al., 2017; Wang et al., 2017a,b).