The three most significant SNPs were BTA1: 1,083,284 (6.04 Kb away from ENSBTAG00000051226), BTA1: 1,146,986 (15.24 Kb away from KCNE2), and BTA1: 1,109,692 (an intron variant of SMIM11A), which explained 2.38, 2.25 and 2.07% of the genetic variance in MS, respectively. The gene discussed is SMIM11; the disease is myeloid sarcoma.