CGAS and colorectal carcinoma: To further characterize the CAFs that downregulate cGAS–STING expression in CRC cells, we compared the basal mRNA expression levels of CAF markers between CAFs that strongly downregulated cGAS–STING expression in CRC cells (s-down-cGAS/STING CAFs) and those that moderately or did not downregulate cGAS–STING expression (m/n-down-cGAS/STING CAFs), based on the median reduction of cGAS–STING expression in CRC cell lines.