Results from the OncoDB database indicated that BRAF, EIF1 AX, FOXE1, KRAS, PDGFRA, PIK3 CA, PTEN, and TERT genes exhibited significantly (p-value < 0.05) higher beta values, indicating increased promoter methylation in thyroid cancer samples compared to normal tissues (Fig. 4A). This evidence concerns the gene FOXE1 and thyroid cancer.