Additionally, the genes were significantly enriched in several cancer-related pathways (Fig. 10D), particularly in"melanoma,""glioma,""endometrial cancer,""EGFR tyrosine kinase inhibitor resistance,"and other cancers such as"acute myeloid leukemia,""renal cell carcinoma,"and"non-small cell lung cancer."These pathways emphasize the potential role of these genes in various cancer types, particularly thyroid cancer. The gene discussed is EGFR; the disease is hereditary clear cell renal cell carcinoma.