Using Iba1 immunostaining in differences radial distances from the infection foci, zone 0–2 (Fig. 3A), we observed an absence of the characteristic ramified microglia in the center of the infection foci (zone 0, Fig. 3B) and an increase in the number of cells in the periphery and adjacent areas (zone 1 & 2, Fig. 3B, C). The gene discussed is AIF1; the disease is infection.