MTOR and cancer: In addition to the dysregulation of the Akt/mTOR/p70S6K pathway, muscle atrophy induced by cancer cachexia is also driven by the hyperactivation of AMP‐activated protein kinase (AMPK), which not only suppresses the mTOR/p70S6K axis, but also activates autophagy and upregulates the transcription of genes involved in muscle protein catabolism via autophagolysosomal and proteasomal systems [2, 32, 33, 34].