This increase can be linked to advancements in diagnostic methods, particularly the use of technetium 99m-pyrophosphate myocardial imaging, which has shown high sensitivity in diagnosing ATTR CA.7 In general, the incidence of wild-type transthyretin (ATTRwt) amyloidosis rose from less than 3% of all cases between 1987 and 2009 to 14% during 2010 to 2015, and further to 25% in more recent years.8 Here, TTR is linked to amyloidosis.