PLA2G5 and idiopathic pulmonary fibrosis: Furthermore, PLA2G5 and PLA2G2, which are associated with inflammation and fibrosis-related pathways, show increased expression in fibroblasts from patients with idiopathic pulmonary fibrosis, thus activating TGF-β, IL-17 signaling pathways, arachidonic acid metabolism, and ECM-receptor interactions26.