FGFR4 promotes tumor progression by binding to its ligands, including FGF19, and upregulates downstream signaling cascades such as Ras-Raf-MAPK and PI3K-AKT to regulate cell growth, differentiation, and survival, together with cell migration by inducing epithelial–mesenchymal transition (EMT) [11]. This evidence concerns the gene FGFR4 and neoplasm.