Compared with those in CT-26/EV cells, CT-26/FGFR4 tumor-derived CAFs exhibited higher expression levels of CAF markers, such as α-SMA, fibroblast activation protein (FAP), PDGF receptor (PDGFR), and vimentin, at both mRNA and protein levels (Fig. 1D). Here, FGFR4 is linked to neoplasm.