Compared with those in CT-26/EV cells, CT-26/FGFR4 tumor-derived CAFs exhibited higher expression levels of CAF markers, such as α-SMA, fibroblast activation protein (FAP), PDGF receptor (PDGFR), and vimentin, at both mRNA and protein levels (Fig. 1D). The gene discussed is VIM; the disease is neoplasm.