This study aimed to replicate this finding in an independent cohort and to assess the specificity and sensitivity of NF-M immunoreactivity in serum samples obtained from BD, systemic lupus erythematosus (SLE), multiple sclerosis (MS), psoriatic arthritis (PsA) and non-Behçet uveitis (NBU) patients as well as healthy donors. This evidence concerns the gene NEFM and Behcet disease.