CXCL2 and gastritis: The network visualization (Fig. 5B) highlighted key genes, including CCL20, CXCL1, CXCL2, and CXCL8, forming highly connected hubs in pathways related to chemokine-mediated signaling and myeloid leukocyte activation, suggested to play a significant role in mediating inflammation and immune cell recruitment, marking the early response to H. pylori infection and the transition to chronic inflammation in gastritis.