Similar to that observed for germinal center B cells, the proportion, but not number of T follicular helper cells, was increased at baseline in SR-BI-/- spleens (P = 0.04, Fig. 3F, gating strategy in Fig. 3E), and this difference was further exacerbated at 16 days post-MHV68 infection (Fig. 3F). Here, SCARB1 is linked to infection.