Mild genitourinary tract infections were observed in both groups: in the SGLT2i cohort, 3 patients (11.1%) developed vaginal candidiasis and 1 patient (3.7%) experienced a urinary tract infection (UTI); in the insulin group, 4 patients (14.8%) developed UTIs and 1 patient (3.7%) had vaginal candidiasis. The gene discussed is INS; the disease is urinary tract infection.