The European Network for the study of PHP (EuroPHPnetwork) in 2016 suggested using new nomenclature inactivating PTH/PTHrP signaling disorder (iPPSD) instead of e.g. PHP and PPHP, POH, Acrodysostosis to refer to common pathogenesis of impairments in PTH and/or PTHrP cAMP-mediated pathway (14). This evidence concerns the gene PTH and progressive osseous heteroplasia.