FZD3 and esophageal squamous cell carcinoma: Conversely, hsa‐miR‐30a‐5p has been shown to enhance 5‐FU sensitivity in esophageal squamous cell carcinoma by downregulating Frizzled Class Receptor 3 (FZD3), a transmembrane receptor involved in the Wnt signaling pathway (Yao et al. 2021).