The hsa‐miR‐22‐3p promotes chemoresistance by targeting Neuroepithelial Cell Transforming 1 (NET1) in breast cancer (Xiao et al. 2018), while it enhances chemosensitivity to cisplatin through the PTEN/PI3K/Akt pathway in gastrointestinal stromal tumor cell lines (Xu et al. 2018). Here, PTEN is linked to gastrointestinal stromal tumor.