VCAM1 and metabolic syndrome: Interestingly, a recent meta‐analysis also reported that probiotic supplementation, particularly multispecies formulations, longer intervention durations (≥ 12 weeks), and applications in patients with metabolic syndrome resulted in a significant reduction of circulating VCAM‐1 levels, suggesting a systemic anti‐inflammatory effect beyond the gut (Rezazadeh et al. 2023).