MYC regulates polyamine biosynthesis in several cancers, including leukemia, lung cancer, neuroblastoma, and breast cancer (Ozfiliz et al., 2015; Koomoa et al., 2013; Funakoshi-Tago et al., 2013; Hogarty et al., 2008; Rimpi and Nilsson, 2007). The gene discussed is MYC; the disease is neuroblastoma.