Recent studies have revealed that acetate can enhance the expression of the Snail Family Transcriptional Repressor 1 (SNAI1), a zinc finger protein involved in downregulating E-cadherin and mediators of EMT, and acyl-CoA synthetase short-chain family member 2 (ACSS2) under glucose limitation in renal carcinoma cells (Yao et al., 2020). The gene discussed is ACSS2; the disease is renal carcinoma.