ACKR3 and colorectal carcinoma: In colorectal carcinoma (CRC), exposure to LPS increases the expression of CXC chemokine receptor 7 (CXCR7) and enhances the proliferation and migration of SW480 and Colo 205 cells via the TLR4/myeloid differential protein (MD-2) pathway (Xu et al., 2011).