FZD2 and gastric cancer: Figure 9C,F show the distinct FZD2 expression patterns across these immune cell types. Violin plots illustrating FZD2 expression revealed high levels in mast cells and fibroblasts (Figures 9G–J), while CD8+ T cells, B cells, plasma cells, and malignant cells showed notably lower expression. Analysis of two GEO datasets further confirmed that FZD2 is highly expressed in fibroblasts. Figures 9K–N present the results of GSEA enrichment analysis, showing up- and downregulated immunogenes in these gastric cancer datasets.