FZD2 and glioblastoma: Furthermore, analysis of disease-free survival (DFS) in the TCGA database indicated that higher FZD2 expression correlated with unfavorable outcomes in KIRC, LGG, MESO, STAD, and uveal melanoma (UVM) (Figures 4C,D), while lower FZD2 expression was linked to poorer DFS in GBM, LUAD, and THCA.