Covalent antibody recruiting molecules (cARMS) are synthetic bifunctional molecules that use a SuFEx electrophile to tether endogenous hapten-specific antibodies with tumour antigens on cancer cells.144 To show proof-of-concept, a native viral peptide epitope (from the herpes simplex virus gD domain) was armed with the sulfonyl fluoride or fluorosulfate warhead and a glutamate urea ligand for the prostate-specific membrane antigen (PSMA). The gene discussed is FOLH1; the disease is neoplasm.