HMGCR and hepatocellular carcinoma: In subgroup analysis (Tables S13 and S14), for the current positive results, decreased expression of HMGCR in blood was associated with a reduced risk of colon cancer (OR = 0.63, 95% CI: 0.42–0.94, p = 0.02) and hepatocellular carcinoma (OR = 0.11, 95% CI: 0.02–0.68, p = 0.02).