FAS and experimental autoimmune encephalomyelitis: Myeloid cell activation during immunization is an important factor for the induction of various experimental disease models based on immunization, such as collagen-induced arthritis and experimental autoimmune encephalomyelitis (Billiau and Matthys, 2011; Rumble et al., 2015; Morell et al., 2017), so functional Fas might be generally required for inflammatory cell activation.