TG and hypothyroidism: Therefore, we hypothesized that both strains contribute to “leaky gut” by exacerbating this inflammation (28), which diminishes the intestinal mucosa’s production and secretion of β-glucuronidase and sulfate lyase, obstructing thyroid hormones’ re-entry into the enterohepatic circulation (29), and prompting an autoimmune response in the thyroid gland (7, 30), leading to hypothyroidism.