Additionally, DNT cells secrete cytokines such as IL-1, IL-8, IL-10, IL-17, TNF-α, and IFN-γ, which can either facilitate immune homeostasis or exacerbate disease activity in conditions such as autoimmune lymphoproliferative syndrome, Sjögren’s syndrome, systemic lupus erythematosus, and psoriasis (40). This evidence concerns the gene IL10 and psoriasis.