Patients with active SLE associated with being positive for any CRP epitope (p<0.05) and displayed a higher number of positive epitopes, but not higher intensity value of positive epitopes, compared to non-active disease (median(IQR): 4(1.8–7) vs. 0.5(0–2.8) epitopes, p<0.01 and 976(678–1117) vs. 737(516–1624) AU, p=0.54 respectively; Figure 2D). Here, CRP is linked to systemic lupus erythematosus.