CRP and rheumatoid arthritis: In a retrospective study (n = 163 RA patients) by Zhao et al. (12) involving ultrasound of the hands/wrists, in addition to demonstrating high intra- and inter-observer reliability (Cohen’s kappa coefficient ranging from 0.72 to 0.97), a significant correlation (correlation coefficient ranging from 0.57 to 0.79) was observed between the sum of the GS and PD scores versus the DAS28-C-reactive protein (DAS28-CRP) (after the study investigators (radiologists) received standardized training on the EULAR-OMERACT scoring system).