Compared with those inPBS-injected mice, the serum levels of the proinflammatory factors TNF-α and IL-17A weresignificantly lower after the injection of MKs into the tail vein of PICS and sepsis modelmice, whereas the serum levels of the chemokine CCL5 were increased (Figure 5C), suggesting that MKs at different stages ofmaturity ( i. The gene discussed is TNF; the disease is Sepsis.