STARD7 and breast cancer: In this context and to better link‐enhanced SAM levels to transcriptional reprogramming seen in breast cancer cells lacking STARD7, we treated MCF7, T47D, MDA‐MB231, or BT549 cells with SAM, which impairs breast cancer proliferation.[33] SAM enhanced H3K27Me3 levels in all tested cell lines (Figure 8B,C).