“Writers” like METTL3 and METTL14 add m6A marks, “erasers” such as fat mass and obesity-associated protein (FTO), ALKBH5 remove them, and “readers” including YTHDF1, YTHDC1 recognize the marks, mediating functional outcomes [26]. The gene discussed is METTL14; the disease is obesity due to melanocortin 4 receptor deficiency.