The primary risk factors included age, duration of dialysis, primary disease, dry skin, serum calcium (Ca), serum phosphorus (P), calcium-phosphorus product, C-reactive protein, intact parathyroid hormone (iPTH), β2-microglobulin (β2-MG), blood urea nitrogen (BUN), and serum creatinine (SCr). The gene discussed is HLA-G; the disease is Dry skin.