NEBL and myocardial disorder: We have identified a number of mutations in a cohort of HCMP patients, including ones in the key HCMP genes - MYBPC3 и MYH7. We have also identified potentially pathologic mutations in genes with no previously established relation to HCMP – ANXA6 and FEM1 A. We have also obtained data that supports the possible role of NEBL in various myocardial diseases.