Zofenopril alleviates vascular constriction pressure by inhibiting the generation of angiotensin II, which indirectly induces endothelial cells to release NO and H2S.439–441 N-acetylcysteine (NAC) is a widely used medication that has been FDA-approved for the treatment of acetaminophen overdose and is utilized as a mucolytic agent for respiratory conditions such as chronic obstructive pulmonary disease (COPD). Here, AGT is linked to chronic obstructive pulmonary disease.