GNAQ and stroke disorder: It occurs in both male and female newborns, with an incidence of approximately 1 in 20,000 to 50,000 live births.[2] SWS is related to a somatic mutation in the GNAQ gene.[3] In patients with SWS, brain involvement typically presents in infancy with seizures, strokes, stroke-like episodes, and a range of neurologic impairments.[4] Standard treatment includes laser therapy for birthmarks and the use of anticonvulsants.