Furthermore, in patients with BLCA, STES, LGG, glioma (GBMLGG), COAD, TGCT, SARC, COAD, READ, KIRC, PRAD, STAD, KIPAN, pheochromocytoma and paraganglioma (PCPG), READ, ACC, LUAD, and KICH, the overexpression of TRIP13 was positively correlated with TMB (Fig. 4E). This evidence concerns the gene TRIP13 and paraganglioma.