Interestingly, in SCLC and retinoblastoma, YAP/TEAD-driven cytostasis is partially mediated via induction of an integrin-αV/β5-Netrin1-UNC5B axis [14,21], whereas down-regulation of Merkel cell polyomavirus large T antigen, likely through indirect mechanisms, is involved in suppressing polyomavirus-positive MCC [24]. Here, YAP1 is linked to retinoblastoma.