However, TAZ is not believed to bind p73 [45], and the anti-cancer role of TAZ in multiple myeloma is likely independent of p73 and TEAD, since mutating the TEAD binding site or WW domain (WW domains mediate YAP/p73 interaction [51]) of TAZ does not affect TAZ function in this context [38]. This evidence concerns the gene YAP1 and AL amyloidosis.