IL18 and alkaline phosphatase measurement: Consistently, the levels of serum inflammatory cytokines such as IL‐1β, IL‐18, IL‐6, IL‐10, IL‐12p70, and tumor necrosis factor‐alpha (TNF‐α) in GSDMD−/− AP group were lower than those in the WT AP group (Figure 3C), suggesting that GSDMD may play a role in promoting inflammation in AP.