Among PWS patients, the plasma levels of VEGF were 1217.97 ± 141.17 pg/mL in those with hypertrophic PWS and 1101.55 ± 166.52 pg/mL in those with flat PWS, also showing a significant difference (t = 2.12, p = 0.04). This evidence concerns the gene VEGFA and Prader-Willi syndrome.