Abbreviations: ASPECTS, Alberta Stroke Program Early CT Score; CT, computed tomography; HDV, hyperdense vessel; ICA, internal carotid artery; MRI, magnetic resonance imaging; mRS, modified Rankin scale; M1, middle cerebral artery first segment; M2, middle cerebral artery second segment; NIHSS, National Institutes of Health Stroke Scale; tPA, tissue plasminogen activator; Tx, therapy; US, ultrasound. This evidence concerns the gene PLAT and Stroke.